Publications (15) ITZIAR MUNETA ARRATE publications

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2025

  1. Ligand bias and inverse agonism on 5-HT2A receptor-mediated modulation of G protein activity in post-mortem human brain

    British Journal of Pharmacology, Vol. 182, Núm. 14, pp. 3320-3335

  2. Synthesis of Diversely Substituted Diethyl (Pyrrolidin-2-Yl)Phosphonates

    Molecules, Vol. 30, Núm. 9

  3. The complexity of G protein-coupled receptor (GPCR) modulation and signalling

    British Journal of Pharmacology

2024

  1. Conformation- and activation-based BRET sensors differentially report on GPCR-G protein coupling

    Science signaling, Vol. 17, Núm. 841, pp. eadi4747

  2. Effects of cannabidiol in post-stroke mood disorders in neonatal rats

    Pediatric Research, Vol. 95, Núm. 7, pp. 1783-1790

  3. Exploring the reactivity of bicyclic α-iminophosphonates to access new imidazoline I2 receptor ligands

    Bioorganic Chemistry, Vol. 142

  4. G protein-specific mechanisms in the serotonin 5-HT2A receptor regulate psychosis-related effects and memory deficits

    Nature communications, Vol. 15, Núm. 1, pp. 4307

2023

  1. 35S]GTPγS (Guanosine-5'-O-(γ-thio)triphosphate-[35S]) Binding Scintillation Proximity Assay Experiments in Postmortem Brain Tissue

    Methods in molecular biology (Clifton, N.J.), Vol. 2687, pp. 31-43

  2. Design, Synthesis, Molecular Docking, and Biological Evaluation of Novel Pimavanserin-Based Analogues as Potential Serotonin 5-HT2A Receptor Inverse Agonists

    Journal of Medicinal Chemistry, Vol. 66, Núm. 13, pp. 9057-9075

  3. The Role of the Dopamine System in Post-Stroke Mood Disorders in Newborn Rats

    International Journal of Molecular Sciences, Vol. 24, Núm. 4

2021

  1. Correction to: Functional approaches to the study of G-protein-coupled receptors in postmortem brain tissue: [35S]GTPγS binding assays combined with immunoprecipitation (Pharmacological Reports, (2021), 73, 4, (1079-1095), 10.1007/s43440-021-00253-z)

    Pharmacological Reports

  2. Evaluación del receptor de serotonina 5-HT2A en esquizofrenia: un ejemplo de investigación traslacional basada en farmacología

    Actualidad en farmacología y terapéutica, Vol. 19, Núm. 3, pp. 154-165

  3. Functional approaches to the study of G-protein-coupled receptors in postmortem brain tissue: [35S]GTPγS binding assays combined with immunoprecipitation

    Pharmacological Reports, Vol. 73, Núm. 4, pp. 1079-1095

2020

  1. Pimavanserin exhibits serotonin 5-HT2A receptor inverse agonism for Gαi1- and neutral antagonism for Gαq/11-proteins in human brain cortex

    European Neuropsychopharmacology, Vol. 36, pp. 83-89

2019

  1. Big Data Challenges Targeting Proteins in GPCR Signaling Pathways; Combining PTML-ChEMBL Models and [35S]GTPγS Binding Assays

    ACS Chemical Neuroscience, Vol. 10, Núm. 11, pp. 4476-4491