REBECA
DIEZ ALARCIA
INVESTIGADOR/A DOCTOR/A PERMANENTE
Publications (46) REBECA DIEZ ALARCIA publications
2024
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Conformation- and activation-based BRET sensors differentially report on GPCR-G protein coupling
Science signaling, Vol. 17, Núm. 841, pp. eadi4747
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Effect of antipsychotic drugs on group II metabotropic glutamate receptor expression and epigenetic control in postmortem brains of schizophrenia subjects
Translational Psychiatry, Vol. 14, Núm. 1
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G protein-specific mechanisms in the serotonin 5-HT2A receptor regulate psychosis-related effects and memory deficits
Nature communications, Vol. 15, Núm. 1, pp. 4307
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Ligand bias and inverse agonism on 5-HT2A receptor-mediated modulation of G protein activity in post-mortem human brain
British Journal of Pharmacology
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The CB1 receptor interacts with cereblon and drives cereblon deficiency-associated memory shortfalls
EMBO Molecular Medicine, Vol. 16, Núm. 4, pp. 755-783
2023
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35S]GTPγS (Guanosine-5'-O-(γ-thio)triphosphate-[35S]) Binding Scintillation Proximity Assay Experiments in Postmortem Brain Tissue
Methods in molecular biology (Clifton, N.J.), Vol. 2687, pp. 31-43
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Design, Synthesis, Molecular Docking, and Biological Evaluation of Novel Pimavanserin-Based Analogues as Potential Serotonin 5-HT2A Receptor Inverse Agonists
Journal of Medicinal Chemistry, Vol. 66, Núm. 13, pp. 9057-9075
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Isolation and Differentiation of Neurons and Glial Cells from Olfactory Epithelium in Living Subjects
Molecular Neurobiology, Vol. 60, Núm. 8, pp. 4472-4487
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Preface
Methods in Molecular Biology
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Selective inhibition of cannabinoid CB1 receptor-evoked signalling by the interacting protein GAP43
Neuropharmacology, Vol. 240
2021
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Adrenergic Modulation With Photochromic Ligands
Angewandte Chemie - International Edition, Vol. 60, Núm. 7, pp. 3625-3631
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Characterization of dopamine D2 receptor coupling to G proteins in postmortem brain of subjects with schizophrenia
Pharmacological Reports, Vol. 73, Núm. 4, pp. 1136-1146
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Correction to: Functional approaches to the study of G-protein-coupled receptors in postmortem brain tissue: [35S]GTPγS binding assays combined with immunoprecipitation (Pharmacological Reports, (2021), 73, 4, (1079-1095), 10.1007/s43440-021-00253-z)
Pharmacological Reports
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Evaluación del receptor de serotonina 5-HT2A en esquizofrenia: un ejemplo de investigación traslacional basada en farmacología
Actualidad en farmacología y terapéutica, Vol. 19, Núm. 3, pp. 154-165
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Functional approaches to the study of G-protein-coupled receptors in postmortem brain tissue: [35S]GTPγS binding assays combined with immunoprecipitation
Pharmacological Reports, Vol. 73, Núm. 4, pp. 1079-1095
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Identification of bip as a cb1 receptor-interacting protein that fine-tunes cannabinoid signaling in the mouse brain
Journal of Neuroscience, Vol. 41, Núm. 38, pp. 7924-7941
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Opposite alterations of 5HT2A receptor brain density in subjects with schizophrenia: relevance of radiotracers pharmacological profile
Translational Psychiatry, Vol. 11, Núm. 1
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Serotonin 2A receptors and cannabinoids
Progress in Brain Research (Elsevier B.V.), pp. 135-175
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α2A- and α2C-adrenoceptor expression and functionality in postmortem prefrontal cortex of schizophrenia subjects
European Neuropsychopharmacology, Vol. 52, pp. 3-11
2020
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Pimavanserin exhibits serotonin 5-HT2A receptor inverse agonism for Gαi1- and neutral antagonism for Gαq/11-proteins in human brain cortex
European Neuropsychopharmacology, Vol. 36, pp. 83-89