Ciencias de la Salud
Campo de conocimiento
Instituto de Química Médica
Madrid, EspañaPublicaciones en colaboración con investigadoras/es de Instituto de Química Médica (13)
2024
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The CB1 receptor interacts with cereblon and drives cereblon deficiency-associated memory shortfalls
EMBO Molecular Medicine, Vol. 16, Núm. 4, pp. 755-783
2021
2015
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New coumarin-based fluorescent melatonin ligands. Design, synthesis and pharmacological characterization
European Journal of Medicinal Chemistry, Vol. 103, pp. 370-373
2014
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Combining rimonabant and fentanyl in a single entity: Preparation and pharmacological results
Drug Design, Development and Therapy, Vol. 8, pp. 263-277
2013
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Description of a bivalent cannabinoid ligand with hypophagic properties
Archiv der Pharmazie, Vol. 346, Núm. 3, pp. 171-179
2010
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Synthesis and pharmacological evaluation of new (E)- and (Z)-3-aryl-4-styryl-1H-pyrazoles as potential cannabinoid ligands
Arkivoc, Vol. 2010, Núm. 10, pp. 226-247
2007
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Synthesis and pharmacological evaluation of chlorinated N-alkyl-3- and -5-(2-hydroxyphenyl)pyrazoles as CB 1 cannabinoid ligands
Monatshefte fur Chemie, Vol. 138, Núm. 8, pp. 797-811
2006
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Synthesis and pharmacological studies of new hybrid derivatives of fentanyl active at the μ-opioid receptor and I2-imidazoline binding sites
Bioorganic and Medicinal Chemistry, Vol. 14, Núm. 19, pp. 6570-6580
2004
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Fentanyl derivatives bearing aliphatic alkaneguanidinium moieties: A new series of hybrid molecules with significant binding affinity for μ-opioid receptors and I2-imidazoline binding sites
Bioorganic and Medicinal Chemistry Letters, Vol. 14, Núm. 2, pp. 491-493
2002
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Guanidinium and aminoimidazolinium derivatives of N-(4-piperidyl)propanamides as potential ligands for μ opioid and I2-imidazoline receptors: Synthesis and pharmacological screening
Bioorganic and Medicinal Chemistry, Vol. 10, Núm. 4, pp. 1009-1018
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I2-imidazoline binding site affinity of a structurally different type of ligands
Bioorganic and Medicinal Chemistry, Vol. 10, Núm. 5, pp. 1525-1533
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Long-acting fentanyl analogues: Synthesis and pharmacology of N-(1-Phenylpyrazolyl)-N-(1-phenylalkyl-4-piperidyl)propanamides
Bioorganic and Medicinal Chemistry, Vol. 10, Núm. 3, pp. 817-827
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Synthesis and opioid activity of new fentanyl analogs
Life Sciences, Vol. 71, Núm. 9, pp. 1023-1034