Publications by the researcher in collaboration with FRANCISCO JAVIER PALACIOS GAMBRA (13)

2022

  1. Multicomponent Synthesis of Unsaturated γ-Lactam Derivatives. Applications as Antiproliferative Agents through the Bioisosterism Approach: Carbonyl vs. Phosphoryl Group

    Pharmaceuticals, Vol. 15, Núm. 5

  2. The design and discovery of topoisomerase I inhibitors as anticancer therapies

    Expert Opinion on Drug Discovery, Vol. 17, Núm. 6, pp. 581-601

2021

  1. A multicomponent protocol for the synthesis of highly functionalized γ-lactam derivatives and their applications as antiproliferative agents

    Pharmaceuticals, Vol. 14, Núm. 8

  2. A patent review of topoisomerase I inhibitors (2016–present)

    Expert Opinion on Therapeutic Patents, Vol. 31, Núm. 6, pp. 473-508

  3. Design, synthesis and cytotoxic evaluation of diphenyl(quinolin-8-yl)phosphine oxides

    Tetrahedron Letters, Vol. 70

  4. Hybrid quinolinyl phosphonates as heterocyclic carboxylate isosteres: Synthesis and biological evaluation against topoisomerase 1b (top1b)

    Pharmaceuticals, Vol. 14, Núm. 8

  5. Simple and fast dna based sensor system for screening of small-molecule compounds targeting eukaryotic topoisomerase 1

    Pharmaceutics, Vol. 13, Núm. 8

2020

  1. Fused 1,5-Naphthyridines: Synthetic Tools and Applications

    Molecules (Basel, Switzerland), Vol. 25, Núm. 15

  2. Synthesis of novel hybrid quinolino[4,3-b][1,5]naphthyridines and quinolino[4,3-b][1,5]naphthyridin-6(5H)-one derivatives and biological evaluation as topoisomerase I inhibitors and antiproliferatives

    European Journal of Medicinal Chemistry, Vol. 195

  3. Synthetic strategies, reactivity and applications of 1,5-naphthyridines

    Molecules, Vol. 25, Núm. 14

2019

  1. Antileishmanial activity of new hybrid tetrahydroquinoline and quinoline derivatives with phosphorus substituents

    European Journal of Medicinal Chemistry, Vol. 162, pp. 18-31

2018

  1. Novel topoisomerase I inhibitors. Syntheses and biological evaluation of phosphorus substituted quinoline derivates with antiproliferative activity

    European Journal of Medicinal Chemistry, Vol. 149, pp. 225-237

2014

  1. Synthesis and biological evaluation of 1,5-naphthyridines as topoisomerase I inhibitors. A new family of antiproliferative agents

    Current Topics in Medicinal Chemistry, Vol. 14, Núm. 23, pp. 2722-2728