Bioquímica y Biología Molecular
Departamento
University of Toronto
Toronto, CanadáPublicaciones en colaboración con investigadoras/es de University of Toronto (14)
2024
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The Human Phenotype Ontology in 2024: phenotypes around the world
Nucleic acids research, Vol. 52, Núm. D1, pp. D1333-D1346
2022
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Engineering pan-HIV-1 neutralization potency through multispecific antibody avidity
Proceedings of the National Academy of Sciences of the United States of America, Vol. 119, Núm. 4
2021
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Focal accumulation of aromaticity at the CDRH3 loop mitigates 4E10 polyreactivity without altering its HIV neutralization profile
iScience, Vol. 24, Núm. 9
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
Autophagy, Vol. 17, Núm. 1, pp. 1-382
2020
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Affinity for the Interface Underpins Potency of Antibodies Operating In Membrane Environments
Cell Reports, Vol. 32, Núm. 7
2019
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Molecular recognition of the native HIV-1 MPER revealed by STED microscopy of single virions
Nature Communications, Vol. 10, Núm. 1
2017
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Diverse Applications of Nanomedicine
ACS Nano, Vol. 11, Núm. 3, pp. 2313-2381
2014
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A unified nomenclature and amino acid numbering for human PTEN
Science Signaling, Vol. 7, Núm. 332
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Structure and immunogenicity of a peptide vaccine, including the complete HIV-1 gp41 2F5 epitope: Implications for antibody recognition mechanism and immunogen design
Journal of Biological Chemistry, Vol. 289, Núm. 10, pp. 6565-6580
2011
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Exclusion of the GNAS locus in PHP-Ib patients with broad GNAS methylation changes: Evidence for an autosomal recessive form of PHP-Ib?
Journal of Bone and Mineral Research, Vol. 26, Núm. 8, pp. 1854-1863
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Interaction of anti-HIV type 1 antibody 2F5 with phospholipid bilayers and its relevance for the mechanism of virus neutralization
AIDS Research and Human Retroviruses, Vol. 27, Núm. 8, pp. 863-876
2010
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Ablation of the complementarity-determining region H3 apex of the anti-HIV-1 broadly neutralizing antibody 2F5 abrogates neutralizing capacity without affecting core epitope binding
Journal of Virology, Vol. 84, Núm. 9, pp. 4136-4147
2009
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Structural Constraints Imposed by the Conserved Fusion Peptide on the HIV-1 gp41 Epitope Recognized by the Broadly Neutralizing Antibody 2F5
Journal of Physical Chemistry B, Vol. 113, Núm. 41, pp. 13626-13637
2008
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Structural Details of HIV-1 Recognition by the Broadly Neutralizing Monoclonal Antibody 2F5: Epitope Conformation, Antigen-Recognition Loop Mobility, and Anion-Binding Site
Journal of Molecular Biology, Vol. 384, Núm. 2, pp. 377-392