Publicaciones en colaboración con investigadoras/es de Trinity College Dublin (13)

2021

  1. Di-aryl guanidinium derivatives: Towards improved α2-Adrenergic affinity and antagonist activity

    European Journal of Medicinal Chemistry, Vol. 209

  2. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

    Autophagy, Vol. 17, Núm. 1, pp. 1-382

2017

  1. Thiophene/thiazole-benzene replacement on guanidine derivatives targeting α2-Adrenoceptors

    European Journal of Medicinal Chemistry, Vol. 138, pp. 38-50

2016

  1. Substituted conformationally restricted guanidine derivatives: Probing the α2-adrenoceptors’ binding pocket

    European Journal of Medicinal Chemistry, Vol. 123, pp. 48-57

2015

  1. α2-adrenoceptor antagonists: Synthesis, pharmacological evaluation, and molecular modeling investigation of pyridinoguanidine, pyridino-2-aminoimidazoline and their derivatives

    Journal of Medicinal Chemistry, Vol. 58, Núm. 2, pp. 963-977

2014

  1. Guanidine-based α2-adrenoceptor ligands: Towards selective antagonist activity

    European Journal of Medicinal Chemistry, Vol. 82, pp. 242-254

2013

  1. Antidepressant-like properties of three new α2-adrenoceptor antagonists

    Neuropharmacology, Vol. 65, pp. 13-19

2008

  1. Guanidine and 2-aminoimidazoline aromatic derivatives as α2-adrenoceptor antagonists. 2. Exploring alkyl linkers for new antidepressants

    Journal of Medicinal Chemistry, Vol. 51, Núm. 11, pp. 3304-3312

  2. Novel synthesis and pharmacological evaluation as α2-adrenoceptor ligands of O-phenylisouronium salts

    Bioorganic and Medicinal Chemistry, Vol. 16, Núm. 17, pp. 8210-8217

  3. PHARMACOLOGICAL EVALUATION OF GUANIDINE AND 2-AMINOIMIDAZOLINE AROMATIC DERIVATIVES AS alpha(2)-ADRENOCEPTOR ANTAGONISTS

    METHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY

2007

  1. Guanidine and 2-aminoimidazoline aromatic derivatives as α2-adrenoceptor antagonists, 1: Toward new antidepressants with heteroatomic linkers

    Journal of Medicinal Chemistry, Vol. 50, Núm. 18, pp. 4516-4527

  2. On the search of new I2-IBS aliphatic ligands: Bis-guanidino carbonyl derivatives

    Bioorganic and Medicinal Chemistry Letters, Vol. 17, Núm. 21, pp. 6009-6012

2002

  1. I2-imidazoline binding site affinity of a structurally different type of ligands

    Bioorganic and Medicinal Chemistry, Vol. 10, Núm. 5, pp. 1525-1533