Facultad de Farmacia
Centro
University of Toronto
Toronto, CanadáPublicaciones en colaboración con investigadoras/es de University of Toronto (31)
2024
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A nonlinear meccano for Alzheimer's emergence by amyloid β-mediated glutamatergic hyperactivity
Neurobiology of Disease, Vol. 194
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Novel risk loci for COVID-19 hospitalization among admixed American populations
eLife, Vol. 13
2023
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A multi-specific, multi-affinity antibody platform neutralizes sarbecoviruses and confers protection against SARS-CoV-2 in vivo
Science translational medicine, Vol. 15, Núm. 697, pp. eadf4549
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A second update on mapping the human genetic architecture of COVID-19
Nature
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Health financing policies during the COVID-19 pandemic and implications for universal health care: a case study of 15 countries
The Lancet Global Health, Vol. 11, Núm. 12, pp. e1964-e1977
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Modular adjuvant-free pan-HLA-DR-immunotargeting subunit vaccine against SARS-CoV-2 elicits broad sarbecovirus-neutralizing antibody responses
Cell Reports, Vol. 42, Núm. 4
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Stimulation of synaptic activity promotes TFEB-mediated clearance of pathological MAPT/Tau in cellular and mouse models of tauopathies
Autophagy, Vol. 19, Núm. 2, pp. 660-677
2022
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Dual Inhibition of Vacuolar-ATPase and TMPRSS2 Is Required for Complete Blockade of SARS-CoV-2 Entry into Cells
Antimicrobial Agents and Chemotherapy, Vol. 66, Núm. 7
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Engineering pan-HIV-1 neutralization potency through multispecific antibody avidity
Proceedings of the National Academy of Sciences of the United States of America, Vol. 119, Núm. 4
2021
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Focal accumulation of aromaticity at the CDRH3 loop mitigates 4E10 polyreactivity without altering its HIV neutralization profile
iScience, Vol. 24, Núm. 9
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
Autophagy, Vol. 17, Núm. 1, pp. 1-382
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Lyophilized, thermostable Spike or RBD immunogenic liposomes induce protective immunity against SARS-CoV-2 in mice
Science Advances, Vol. 7, Núm. 49
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Multiscale interactome analysis coupled with off-target drug predictions reveals drug repurposing candidates for human coronavirus disease
Scientific Reports, Vol. 11, Núm. 1
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Multivalency transforms SARS-CoV-2 antibodies into ultrapotent neutralizers
Nature Communications, Vol. 12, Núm. 1
2020
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Affinity for the Interface Underpins Potency of Antibodies Operating In Membrane Environments
Cell Reports, Vol. 32, Núm. 7
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Mutant p53 induces Golgi tubulo-vesiculation driving a prometastatic secretome
Nature Communications, Vol. 11, Núm. 1
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Structural characterization of the ICOS/ICOS-L immune complex reveals high molecular mimicry by therapeutic antibodies
Nature Communications, Vol. 11, Núm. 1
2019
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3D Bioprinting in Skeletal Muscle Tissue Engineering
Small, Vol. 15, Núm. 24
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Molecular recognition of the native HIV-1 MPER revealed by STED microscopy of single virions
Nature Communications, Vol. 10, Núm. 1
2018
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Synaptic activity protects against AD and FTD-like pathology via autophagic-lysosomal degradation
Molecular Psychiatry, Vol. 23, Núm. 6, pp. 1530-1540