Facultad de Farmacia
Centro
MARIA GLORIA
RUBIALES ALCAINE
Investigador/a en el periodo 2000-2020
Publicaciones en las que colabora con MARIA GLORIA RUBIALES ALCAINE (61)
2021
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A patent review of topoisomerase I inhibitors (2016–present)
Expert Opinion on Therapeutic Patents, Vol. 31, Núm. 6, pp. 473-508
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Fused chromeno and quinolino[1,8]naphthyridines: Synthesis and biological evaluation as topoisomerase I inhibitors and antiproliferative agents
Bioorganic and Medicinal Chemistry, Vol. 40
2020
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Fused 1,5-Naphthyridines: Synthetic Tools and Applications
Molecules (Basel, Switzerland), Vol. 25, Núm. 15
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Novel phosphine sulphide gold(i) complexes: topoisomerase I inhibitors and antiproliferative agents
Dalton Transactions, Vol. 49, Núm. 23, pp. 7852-7861
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Synthesis of novel hybrid quinolino[4,3-b][1,5]naphthyridines and quinolino[4,3-b][1,5]naphthyridin-6(5H)-one derivatives and biological evaluation as topoisomerase I inhibitors and antiproliferatives
European Journal of Medicinal Chemistry, Vol. 195
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Synthetic strategies, reactivity and applications of 1,5-naphthyridines
Molecules, Vol. 25, Núm. 14
2019
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Antileishmanial activity of new hybrid tetrahydroquinoline and quinoline derivatives with phosphorus substituents
European Journal of Medicinal Chemistry, Vol. 162, pp. 18-31
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Reaction of phosphinyl nitrosoalkenes with electron-rich heterocycles
Phosphorus, Sulfur and Silicon and the Related Elements, Vol. 194, Núm. 4-6, pp. 545-549
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Straightforward synthesis and biological evaluation as topoisomerase I inhibitors and antiproliferative agents of hybrid Chromeno[4,3-b][1,5]Naphthyridines and Chromeno[4,3-b][1,5]Naphthyridin-6-ones
European Journal of Medicinal Chemistry, Vol. 178, pp. 752-766
2018
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Density Functional Theory Study on the Demethylation Reaction between Methylamine, Dimethylamine, Trimethylamine, and Tamoxifen Catalyzed by a Fe(IV)-Oxo Porphyrin Complex
Journal of Physical Chemistry A, Vol. 122, Núm. 6, pp. 1658-1671
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Novel topoisomerase I inhibitors. Syntheses and biological evaluation of phosphorus substituted quinoline derivates with antiproliferative activity
European Journal of Medicinal Chemistry, Vol. 149, pp. 225-237
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Substituted 1,5-naphthyridine derivatives as novel antileishmanial agents. Synthesis and biological evaluation
European Journal of Medicinal Chemistry, Vol. 152, pp. 137-147
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Synthesis of novel antiproliferative hybrid bis-(3-indolyl)methane phosphonate derivatives
European Journal of Medicinal Chemistry, Vol. 158, pp. 874-883
2017
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ACTIVE METHODOLOGIES FOR SOLVING CLINICAL CASES: STUDENT'S FEEDBACK
10TH INTERNATIONAL CONFERENCE OF EDUCATION, RESEARCH AND INNOVATION (ICERI2017)
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Advantages of an optical nanosensor system for the mechanistic analysis of a novel topoisomerase i targeting drug: A case study
Nanoscale, Vol. 9, Núm. 5, pp. 1886-1895
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Reaction of phosphinylated nitrosoalkenes with electron-rich heterocycles. Electrophilic aromatic substitution vs. cycloaddition
Organic and Biomolecular Chemistry, Vol. 15, Núm. 3, pp. 662-671
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Reliable Synthesis of Phosphino- and Phosphine Sulfide-1,2,3,4-Tetrahydroquinolines and Phosphine Sulfide Quinolines
European Journal of Organic Chemistry, Vol. 2017, Núm. 20, pp. 2916-2924
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Study of the Hetero-[4+2]-Cycloaddition Reaction of Aldimines and Alkynes. Synthesis of 1,5-Naphthyridine and Isoindolone Derivatives
Journal of Organic Chemistry, Vol. 82, Núm. 12, pp. 6379-6387
2016
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Antileishmanial effect of new indeno-1,5-naphthyridines, selective inhibitors of Leishmania infantum type IB DNA topoisomerase
European Journal of Medicinal Chemistry, Vol. 124, pp. 740-749
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Synthesis and biological evaluation of indeno[1,5]naphthyridines as topoisomerase i (TopI) inhibitors with antiproliferative activity
European Journal of Medicinal Chemistry, Vol. 115, pp. 179-190