PATRICIA
ASPICHUETA CELAA
PROFESORADO PLENO
Ikerbasque, Fundación Vasca para la Ciencia
Bilbao, EspañaPublicaciones en colaboración con investigadoras/es de Ikerbasque, Fundación Vasca para la Ciencia (21)
2023
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Hepatic levels of S-adenosylmethionine regulate the adaptive response to fasting
Cell Metabolism, Vol. 35, Núm. 8, pp. 1373-1389.e8
2022
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Cholangiocarcinoma progression depends on the uptake and metabolization of extracellular lipids
Hepatology, Vol. 76, Núm. 6, pp. 1617-1633
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Genetics, pathobiology and therapeutic opportunities of polycystic liver disease
Nature Reviews Gastroenterology and Hepatology, Vol. 19, Núm. 9, pp. 585-604
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Methionine adenosyltransferase 1a antisense oligonucleotides activate the liver-brown adipose tissue axis preventing obesity and associated hepatosteatosis
Nature Communications, Vol. 13, Núm. 1
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TREM-2 plays a protective role in cholestasis by acting as a negative regulator of inflammation
Journal of Hepatology, Vol. 77, Núm. 4, pp. 991-1004
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Targeting E2F Sensitizes Prostate Cancer Cells to Drug-Induced Replication Stress by Promoting Unscheduled CDK1 Activity
Cancers, Vol. 14, Núm. 19
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Targeting NAE1-mediated protein hyper-NEDDylation halts cholangiocarcinogenesis and impacts on tumor-stroma crosstalk in experimental models
Journal of Hepatology, Vol. 77, Núm. 1, pp. 177-190
2021
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E2F1 and E2F2-mediated repression of CPT2 establishes a lipid-rich tumor-promoting environment
Cancer Research, Vol. 81, Núm. 11, pp. 2874-2887
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Inhibition of NAE-dependent protein hyper-NEDDylation in cystic cholangiocytes halts cystogenesis in experimental models of polycystic liver disease
United European Gastroenterology Journal, Vol. 9, Núm. 7, pp. 848-859
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Neddylation inhibition ameliorates steatosis in NAFLD by boosting hepatic fatty acid oxidation via the DEPTOR-mTOR axis
Molecular Metabolism, Vol. 53
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TREM-2 defends the liver against hepatocellular carcinoma through multifactorial protective mechanisms
Gut, Vol. 70, Núm. 7, pp. 1345-1361
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Targeting UBC9-mediated protein hyper-SUMOylation in cystic cholangiocytes halts polycystic liver disease in experimental models
Journal of Hepatology, Vol. 74, Núm. 2, pp. 394-406
2020
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Birc6 is associated with vulnerability of carotid atherosclerotic plaque
International Journal of Molecular Sciences, Vol. 21, Núm. 24, pp. 1-13
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Silencing hepatic MCJ attenuates non-alcoholic fatty liver disease (NAFLD) by increasing mitochondrial fatty acid oxidation
Nature Communications, Vol. 11, Núm. 1
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Targeting Hepatic Glutaminase 1 Ameliorates Non-alcoholic Steatohepatitis by Restoring Very-Low-Density Lipoprotein Triglyceride Assembly
Cell Metabolism, Vol. 31, Núm. 3, pp. 605-622.e10
2019
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miR-873-5p targets mitochondrial GNMT-Complex II interface contributing to non-alcoholic fatty liver disease
Molecular Metabolism, Vol. 29, pp. 40-54
2017
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Hepatic p63 regulates steatosis via IKKβ/ER stress
Nature Communications, Vol. 8
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Role of aramchol in steatohepatitis and fibrosis in mice
Hepatology Communications, Vol. 1, Núm. 9, pp. 911-927
2016
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Methionine and S-adenosylmethionine levels are critical regulators of PP2A activity modulating lipophagy during steatosis
Journal of Hepatology, Vol. 64, Núm. 2, pp. 409-418
2015
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Proteomic and lipidomic analysis of primary mouse hepatocytes exposed to metal and metal oxide nanoparticles
Journal of Integrated OMICS, Vol. 5, Núm. 1, pp. 44-57