Publicaciones (36) Publicaciones de JUAN MANUEL GONZALEZ MAÑAS

2019

  1. The isolation of new pore-forming toxins from the sea anemone actinia fragacea provides insights into the mechanisms of actinoporin evolution

    Toxins, Vol. 11, Núm. 7

2016

  1. Erratum: Fatty acids' double role in the prebiotic formation of a hydrophobic dipeptide(Chemical Science (2016) 10.1039/c5sc04796j)

    Chemical Science

  2. Fatty acids' double role in the prebiotic formation of a hydrophobic dipeptide

    Chemical Science, Vol. 7, Núm. 5, pp. 3406-3413

  3. Identification of a membrane-bound prepore species clarifies the lytic mechanism of actinoporins

    Journal of Biological Chemistry, Vol. 291, Núm. 37, pp. 19210-19219

2015

  1. A pore-forming toxin requires a specific residue for its activity in membranes with particular physicochemical properties

    Journal of Biological Chemistry, Vol. 290, Núm. 17, pp. 10850-10861

  2. Functional characterization of Val60, a key residue involved in the membrane-oligomerization of fragaceatoxin C, an actinoporin from Actinia fragacea

    FEBS Letters, Vol. 589, Núm. 15, pp. 1840-1846

  3. Structural basis for self-assembly of a cytolytic pore lined by protein and lipid

    Nature Communications, Vol. 6

2012

  1. Pores of the toxin FraC assemble into 2D hexagonal clusters in both crystal structures and model membranes

    Journal of Structural Biology, Vol. 180, Núm. 2, pp. 312-317

2011

  1. Structural insights into the oligomerization and architecture of eukaryotic membrane pore-forming toxins

    Structure, Vol. 19, Núm. 2, pp. 181-191

2009

  1. Crystallization and preliminary crystallographic analysis of fragaceatoxin C, a pore-forming toxin from the sea anemone actinia fragacea

    Acta Crystallographica Section F: Structural Biology and Crystallization Communications, Vol. 65, Núm. 4, pp. 357-360

  2. Purification, cloning and characterization of fragaceatoxin C, a novel actinoporin from the sea anemone Actinia fragacea

    Toxicon, Vol. 54, Núm. 6, pp. 869-880

2007

  1. Effect of sphingomyelin and cholesterol on the interaction of St II with lipidic interfaces

    Toxicon, Vol. 49, Núm. 1, pp. 68-81

2004

  1. Lipid phase coexistence favors membrane insertion of equinatoxin-II, a pore-forming toxin from Actinia equina

    Journal of Biological Chemistry, Vol. 279, Núm. 33, pp. 34209-34216

  2. Membrane insertion of the N-terminal α-helix of equinatoxin II, a sea anemone cytolytic toxin

    Biochemical Journal, Vol. 384, Núm. 2, pp. 421-428

  3. Pore formation by equinatoxin, a eukaryotic pore-forming toxin, requires a flexible N-terminal region and a stable β-sandwich

    Journal of Biological Chemistry, Vol. 279, Núm. 45, pp. 46509-46517

2002

  1. Two-step membrane binding by equinatoxin II, a pore-forming toxin from the sea anemone, involves an exposed aromatic cluster and a flexible helix

    Journal of Biological Chemistry, Vol. 277, Núm. 44, pp. 41916-41924

2001

  1. Differential interaction of equinatoxin II with model membranes in response to lipid composition

    Biophysical Journal, Vol. 80, Núm. 3, pp. 1343-1353

1998

  1. Interaction of wheat α-thionin with large unilamellar vesicles

    Protein Science, Vol. 7, Núm. 12, pp. 2567-2577

1997

  1. Differential effects of five types of antipathogenic plant peptides on model membranes

    FEBS Letters, Vol. 410, Núm. 2-3, pp. 338-342

1996

  1. Membrane topology of the colicin A pore-forming domain analyzed by disulfide bond engineering

    Journal of Biological Chemistry, Vol. 271, Núm. 26, pp. 15401-15406