Publicaciones (18) Publicaciones de GORKA GEREÑU LOPETEGI

2024

  1. Impaired astrocytic synaptic function by peripheral cholesterol metabolite 27-hydroxycholesterol

    Frontiers in Cellular Neuroscience, Vol. 18

2022

  1. Defects of Nutrient Signaling and Autophagy in Neurodegeneration

    Frontiers in Cell and Developmental Biology, Vol. 10

  2. Senescence plays a role in myotonic dystrophy type 1

    JCI insight, Vol. 7, Núm. 19

  3. Serum Thioredoxin-80 is associated with age, ApoE4, and neuropathological biomarkers in Alzheimer’s disease: a potential early sign of AD

    Alzheimer's Research and Therapy, Vol. 14, Núm. 1

  4. Targeting the Ubiquitin-Proteasome System in Limb-Girdle Muscular Dystrophy With CAPN3 Mutations

    Frontiers in Cell and Developmental Biology, Vol. 10

2021

  1. High levels of 27-hydroxycholesterol results in synaptic plasticity alterations in the hippocampus

    Scientific Reports, Vol. 11, Núm. 1

  2. The skeletal muscle emerges as a new disease target in amyotrophic lateral sclerosis

    Journal of Personalized Medicine, Vol. 11, Núm. 7

  3. Thioredoxin-80 protects against amyloid-beta pathology through autophagic-lysosomal pathway regulation

    Molecular Psychiatry, Vol. 26, Núm. 4, pp. 1410-1423

2020

  1. A comprehensive serum lipidome profiling of amyotrophic lateral sclerosis

    Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, Vol. 21, Núm. 3-4, pp. 252-262

2018

  1. Connecting the brain cholesterol and renin–angiotensin systems: potential role of statins and RAS-modifying medications in dementia

    Journal of Internal Medicine, Vol. 284, Núm. 6, pp. 620-642

2017

  1. Modulation of BDNF cleavage by plasminogen-activator inhibitor-1 contributes to Alzheimer's neuropathology and cognitive deficits

    Biochimica et Biophysica Acta - Molecular Basis of Disease, Vol. 1863, Núm. 4, pp. 991-1001

2016

  1. Down-regulation of glutamatergic terminals (VGLUT1) driven by Aβ in Alzheimer's disease

    Hippocampus, Vol. 26, Núm. 10, pp. 1303-1312

2015

  1. Curcumin/Melatonin Hybrid 5-(4-Hydroxy-phenyl)-3-oxo-pentanoic Acid [2-(5-Methoxy-1H-indol-3-yl)-ethyl]-amide Ameliorates AD-Like Pathology in the APP/PS1 Mouse Model

    ACS Chemical Neuroscience, Vol. 6, Núm. 8, pp. 1393-1399

2013

  1. Early cognitive stimulation compensates for memory and pathological changes in Tg2576 mice

    Biochimica et Biophysica Acta - Molecular Basis of Disease, Vol. 1832, Núm. 6, pp. 837-847

  2. Mineralocorticoid Receptor Activation Induces Insulin Resistance Through c-Jun N-terminal kinases in Response to Chronic Corticosterone: Cognitive Implications

    Journal of Neuroendocrinology, Vol. 25, Núm. 4, pp. 350-356

  3. Propranolol reduces cognitive deficits, amyloid and tau pathology in Alzheimer's transgenic mice

    International Journal of Neuropsychopharmacology

2012

  1. Cholinergic denervation exacerbates amyloid pathology and induces hippocampal atrophy in Tg2576 mice

    Neurobiology of Disease, Vol. 48, Núm. 3, pp. 439-446

  2. Mechanisms involved in BACE upregulation associated to stress

    Current Alzheimer Research, Vol. 9, Núm. 7, pp. 822-829