IZORTZE
SANTIN GOMEZ
PROFESORADO AGREGADO
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Université Libre de Bruxelles
Bruselas, BélgicaPublicaciones en colaboración con investigadoras/es de Université Libre de Bruxelles (14)
2023
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A long non-coding RNA that harbors a SNP associated with type 2 diabetes regulates the expression of TGM2 gene in pancreatic beta cells
Frontiers in Endocrinology, Vol. 14
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LncRNA ARGI Contributes to Virus-Induced Pancreatic β Cell Inflammation Through Transcriptional Activation of IFN-Stimulated Genes
Advanced Science, Vol. 10, Núm. 25
2020
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The T1D-associated lncRNA Lnc13 modulates human pancreatic β cell inflammation by allele-specific stabilization of STAT1 mRNA
Proceedings of the National Academy of Sciences of the United States of America, Vol. 117, Núm. 16, pp. 9022-9031
2019
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DEXI, a candidate gene for type 1 diabetes, modulates rat and human pancreatic beta cell inflammation via regulation of the type I IFN/STAT signalling pathway
Diabetologia, Vol. 62, Núm. 3, pp. 459-472
2016
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Pancreatic beta cell survival and signaling pathways: Effects of type 1 diabetes-associated genetic variants
Methods in Molecular Biology (Humana Press Inc.), pp. 21-54
2015
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TYK2, a candidate gene for type 1 diabetes, modulates apoptosis and the innate immune response in human pancreatic β-cells
Diabetes, Vol. 64, Núm. 11, pp. 3808-3817
2014
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BACH2, a candidate risk gene for type 1 diabetes, regulates apoptosis in pancreatic β-cells via JNK1 modulation and crosstalk with the candidate gene PTPN2
Diabetes, Vol. 63, Núm. 7, pp. 2516-2527
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IL-17A increases the expression of proinflammatory chemokines in human pancreatic islets
Diabetologia, Vol. 57, Núm. 3, pp. 502-511
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RNA sequencing identifies dysregulation of the human pancreatic islet transcriptome by the saturated fatty acid palmitate
Diabetes, Vol. 63, Núm. 6, pp. 1978-1993
2013
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Candidate genes for type 1 diabetes modulate pancreatic islet inflammation and β-cell apoptosis
Diabetes, Obesity and Metabolism, Vol. 15, Núm. S3, pp. 71-81
2012
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The human pancreatic islet transcriptome: Expression of candidate genes for type 1 diabetes and the impact of pro-inflammatory cytokines
PLoS Genetics, Vol. 8, Núm. 3
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The transcription factor C/EBP delta has anti-apoptotic and anti-inflammatory roles in pancreatic beta cells
PLoS ONE, Vol. 7, Núm. 2
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USP18 is a key regulator of the interferon-driven gene network modulating pancreatic beta cell inflammation and apoptosis
Cell Death and Disease, Vol. 3, Núm. 11
2011
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PTPN2, a candidate gene for type 1 diabetes, modulates pancreatic β-cell apoptosis via regulation of the BH3-only protein bim
Diabetes, Vol. 60, Núm. 12, pp. 3279-3288