Publicaciones en colaboración con investigadoras/es de University of Toronto (12)

2023

  1. A multi-specific, multi-affinity antibody platform neutralizes sarbecoviruses and confers protection against SARS-CoV-2 in vivo

    Science translational medicine, Vol. 15, Núm. 697, pp. eadf4549

  2. Modular adjuvant-free pan-HLA-DR-immunotargeting subunit vaccine against SARS-CoV-2 elicits broad sarbecovirus-neutralizing antibody responses

    Cell Reports, Vol. 42, Núm. 4

2022

  1. Dual Inhibition of Vacuolar-ATPase and TMPRSS2 Is Required for Complete Blockade of SARS-CoV-2 Entry into Cells

    Antimicrobial Agents and Chemotherapy, Vol. 66, Núm. 7

  2. Engineering pan-HIV-1 neutralization potency through multispecific antibody avidity

    Proceedings of the National Academy of Sciences of the United States of America, Vol. 119, Núm. 4

2021

  1. Focal accumulation of aromaticity at the CDRH3 loop mitigates 4E10 polyreactivity without altering its HIV neutralization profile

    iScience, Vol. 24, Núm. 9

  2. Lyophilized, thermostable Spike or RBD immunogenic liposomes induce protective immunity against SARS-CoV-2 in mice

    Science Advances, Vol. 7, Núm. 49

  3. Multiscale interactome analysis coupled with off-target drug predictions reveals drug repurposing candidates for human coronavirus disease

    Scientific Reports, Vol. 11, Núm. 1

  4. Multivalency transforms SARS-CoV-2 antibodies into ultrapotent neutralizers

    Nature Communications, Vol. 12, Núm. 1

2020

  1. Affinity for the Interface Underpins Potency of Antibodies Operating In Membrane Environments

    Cell Reports, Vol. 32, Núm. 7

  2. Structural characterization of the ICOS/ICOS-L immune complex reveals high molecular mimicry by therapeutic antibodies

    Nature Communications, Vol. 11, Núm. 1

2019

  1. Molecular recognition of the native HIV-1 MPER revealed by STED microscopy of single virions

    Nature Communications, Vol. 10, Núm. 1

2014

  1. Structure and immunogenicity of a peptide vaccine, including the complete HIV-1 gp41 2F5 epitope: Implications for antibody recognition mechanism and immunogen design

    Journal of Biological Chemistry, Vol. 289, Núm. 10, pp. 6565-6580