Publicaciones en colaboración con investigadoras/es de Ikerbasque, Fundación Vasca para la Ciencia (25)

2023

  1. Structural and functional insights into the delivery of a bacterial Rhs pore-forming toxin to the membrane

    Nature Communications, Vol. 14, Núm. 1

2022

  1. Fine-tuning of the Hsc70-based Human Protein Disaggregase Machinery by the Distinctive C-terminal Extension of Apg2

    Journal of Molecular Biology, Vol. 434, Núm. 22

  2. The P. aeruginosa effector Tse5 forms membrane pores disrupting the membrane potential of intoxicated bacteria

    Communications Biology, Vol. 5, Núm. 1

2021

  1. Identification of Tse8 as a Type VI secretion system toxin from Pseudomonas aeruginosa that targets the bacterial transamidosome to inhibit protein synthesis in prey cells

    Nature Microbiology, Vol. 6, Núm. 9, pp. 1199-1210

2020

  1. Dissecting the Structural and Chemical Determinants of the "open-To-Closed" Motion in the Mannosyltransferase PimA from Mycobacteria

    Biochemistry, Vol. 59, Núm. 32, pp. 2934-2945

  2. Structural insights into Pseudomonas aeruginosa Type six secretion system exported effector 8

    Journal of Structural Biology, Vol. 212, Núm. 3

  3. The allosteric control mechanism of bacterial glycogen biosynthesis disclosed by cryoEM

    Current Research in Structural Biology, Vol. 2, pp. 89-103

2019

  1. Quick-soaking of crystals reveals unprecedented insights into the catalytic mechanism of glycosyltransferases

    Methods in Enzymology (Academic Press Inc.), pp. 261-279

  2. Regulation of Human Hsc70 ATPase and Chaperone Activities by Apg2: Role of the Acidic Subdomain

    Journal of Molecular Biology, Vol. 431, Núm. 2, pp. 444-461

  3. Structure-function relationships underlying the dual N-acetylmuramic and N-acetylglucosamine specificities of the bacterial peptidoglycan deacetylase PdaC

    Journal of Biological Chemistry, Vol. 294, Núm. 50, pp. 19066-19080

2018

  1. The Molecular Mechanism of Substrate Recognition and Catalysis of the Membrane Acyltransferase PatA from Mycobacteria

    ACS Chemical Biology, Vol. 13, Núm. 1, pp. 131-140

2017

  1. Structural Snapshots and Loop Dynamics along the Catalytic Cycle of Glycosyltransferase GpgS

    Structure, Vol. 25, Núm. 7, pp. 1034-1044.e3

  2. Structural basis of phosphatidyl-myo-inositol mannosides biosynthesis in mycobacteria

    Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, Vol. 1862, Núm. 11, pp. 1355-1367

  3. The antibacterial prodrug activator Rv2466c is a mycothiol-dependent reductase in the oxidative stress response of Mycobacterium tuberculosis

    Journal of Biological Chemistry, Vol. 292, Núm. 32, pp. 13097-13110

2016

  1. Structural Basis of Glycogen Biosynthesis Regulation in Bacteria

    Structure, Vol. 24, Núm. 9, pp. 1613-1622

  2. Structural basis for selective recognition of acyl chains by the membrane-associated acyltransferase PatA

    Nature Communications, Vol. 7

  3. The conformational plasticity of glycosyltransferases

    Current Opinion in Structural Biology, Vol. 40, pp. 23-32

2015

  1. A Native Ternary Complex Trapped in a Crystal Reveals the Catalytic Mechanism of a Retaining Glycosyltransferase

    Angewandte Chemie - International Edition, Vol. 54, Núm. 34, pp. 9898-9902

  2. Secondary structure reshuffling modulates glycosyltransferase function at the membrane

    Nature Chemical Biology, Vol. 11, Núm. 1, pp. 16-18

  3. The redox state regulates the conformation of Rv2466c to activate the antitubercular prodrug TP053

    Journal of Biological Chemistry, Vol. 290, Núm. 52, pp. 31077-31089