JUAN MANUEL
RAMIREZ SANCHEZ
PROFESORADO ADJUNTO
Ikerbasque, Fundación Vasca para la Ciencia
Bilbao, EspañaPublicaciones en colaboración con investigadoras/es de Ikerbasque, Fundación Vasca para la Ciencia (19)
2024
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Biotin-Based Strategies to Explore the World of Ubiquitin and Ubiquitin-Like Modifiers
ChemBioChem, Vol. 25, Núm. 6
2023
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Linoleic acid improves PIEZO2 dysfunction in a mouse model of Angelman Syndrome
Nature Communications, Vol. 14, Núm. 1
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P-Rex1 is a novel substrate of the E3 ubiquitin ligase Malin associated with Lafora disease
Neurobiology of Disease, Vol. 177
2022
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HERC2 deficiency activates C-RAF/MKK3/p38 signalling pathway altering the cellular response to oxidative stress
Cellular and Molecular Life Sciences, Vol. 79, Núm. 11
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Identification of substrates for human deubiquitinating enzymes (DUBs): An up-to-date review and a case study for neurodevelopmental disorders
Seminars in Cell and Developmental Biology, Vol. 132, pp. 120-131
2021
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A proteomic approach for systematic mapping of substrates of human deubiquitinating enzymes
International Journal of Molecular Sciences, Vol. 22, Núm. 9
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The ubiquitin ligase Ariadne-1 regulates neurotransmitter release via ubiquitination of NSF
Journal of Biological Chemistry, Vol. 296
2020
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How to Inactivate Human Ubiquitin E3 Ligases by Mutation
Frontiers in Cell and Developmental Biology, Vol. 8
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Mass spectrometry-based characterization of Ub- and UbL-modified proteins
Methods in Molecular Biology (Humana Press Inc.), pp. 265-276
2019
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Detailed dissection of UBe3A-mediated DDI1 ubiquitination
Frontiers in Physiology, Vol. 10, Núm. MAY
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Impaired proteostasis in rare neurological diseases
Seminars in Cell and Developmental Biology, Vol. 93, pp. 164-177
2018
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Neuronal proteomic analysis of the ubiquitinated substrates of the disease-linked E3 ligases parkin and Ube3a
BioMed Research International, Vol. 2018
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Quantitative proteomics reveals neuronal ubiquitination of Rngo/Ddi1 and several proteasomal subunits by Ube3a, accounting for the complexity of Angelman syndrome
Human Molecular Genetics, Vol. 27, Núm. 11, pp. 1955-1971
2017
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A comprehensive platform for the analysis of ubiquitin-like protein modifications using in vivo biotinylation
Scientific Reports, Vol. 7
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In vivo strategies to isolate and characterize the neuronal ubiquitinated proteome
Neuromethods (Humana Press Inc.), pp. 179-189
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Quantitative proteomic analysis of Parkin substrates in Drosophila neurons
Molecular Neurodegeneration, Vol. 12, Núm. 1
2015
2014
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Ube3a, the E3 ubiquitin ligase causing Angelman syndrome and linked to autism, regulates protein homeostasis through the proteasomal shuttle Rpn10
Cellular and Molecular Life Sciences, Vol. 71, Núm. 14, pp. 2747-2758
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Ubiquitin profiling in liver using a transgenic mouse with biotinylated ubiquitin
Journal of Proteome Research, Vol. 13, Núm. 6, pp. 3016-3026