Publicaciones (48) Publicaciones de IVAN UBARRECHENA BELANDIA

2024

  1. Cryo-EM structure of the Rev1–Polζ holocomplex reveals the mechanism of their cooperativity in translesion DNA synthesis

    Nature Structural and Molecular Biology

2023

  1. Structural and functional insights into the delivery of a bacterial Rhs pore-forming toxin to the membrane

    Nature Communications, Vol. 14, Núm. 1

2022

  1. Cryo-EM structure of translesion DNA synthesis polymerase ζ with a base pair mismatch

    Nature Communications, Vol. 13, Núm. 1

2021

  1. Conformational plasticity underlies membrane fusion induced by an HIV sequence juxtaposed to the lipid envelope

    Scientific Reports, Vol. 11, Núm. 1

2020

  1. Presenilin1 familial Alzheimer disease mutants inactivate EFNB1-and BDNF-dependent neuroprotection against excitotoxicity by affecting neuroprotective complexes of N-methyl-d-Aspartate receptor

    Brain Communications, Vol. 2, Núm. 2

  2. Structural basis for active single and double ring complexes in human mitochondrial Hsp60-Hsp10 chaperonin

    Nature Communications, Vol. 11, Núm. 1

  3. Structure and mechanism of B-family DNA polymerase ζ specialized for translesion DNA synthesis

    Nature Structural and Molecular Biology, Vol. 27, Núm. 10, pp. 913-924

  4. Substrate interaction inhibits γ-secretase production of amyloid-β peptides

    Chemical Communications, Vol. 56, Núm. 17, pp. 2578-2581

  5. Substrate–Enzyme Interactions in Intramembrane Proteolysis: γ-Secretase as the Prototype

    Frontiers in Molecular Neuroscience, Vol. 13

2019

  1. Vitamin B 12 modulates Parkinson’s disease LRRK2 kinase activity through allosteric regulation and confers neuroprotection

    Cell Research, Vol. 29, Núm. 4, pp. 313-329

  2. CD46 facilitates entry and dissemination of human cytomegalovirus

    Nature Communications, Vol. 10, Núm. 1

  3. Cryo-EM structure and dynamics of eukaryotic DNA polymerase δ holoenzyme

    Nature Structural and Molecular Biology, Vol. 26, Núm. 10, pp. 955-962

2018

  1. Coupled Transmembrane Substrate Docking and Helical Unwinding in Intramembrane Proteolysis of Amyloid Precursor Protein

    Scientific Reports, Vol. 8, Núm. 1

  2. Design and validation of an open-source modular Microplate Photoirradiation System for high-Throughput photobiology experiments

    PLoS ONE, Vol. 13, Núm. 10

  3. Functional variants in the LRRK2 gene confer shared effects on risk for Crohn's disease and Parkinson's disease

    Science Translational Medicine, Vol. 10, Núm. 423

  4. Unwinding of the Substrate Transmembrane Helix in Intramembrane Proteolysis

    Biophysical Journal, Vol. 114, Núm. 7, pp. 1579-1589

2017

  1. A New Method to Determine the Transmembrane Conformation of Substrates in Intramembrane Proteolysis by Deep-UV Resonance Raman Spectroscopy

    Methods in Enzymology (Academic Press Inc.), pp. 207-228

2016

  1. Structural model of the dimeric Parkinson's protein LRRK2 reveals a compact architecture involving distant interdomain contacts

    Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Núm. 30, pp. E4357-E4366

2015

  1. Sparse and incomplete factorial matrices to screen membrane protein 2D crystallization

    Journal of Structural Biology, Vol. 189, Núm. 2, pp. 123-134

2013

  1. High-throughput methods for electron crystallography

    Methods in Molecular Biology (Humana Press Inc.), pp. 273-296