Reacciones Multicomponente Asimétricas para la preparación de pequeñas moléculas de aplicación en Química Médica: agentes anticancerosos y antimicrobianos - GIC 21/020
Publicaciones (19) Publicaciones en las que ha participado algún/a investigador/a
2024
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Antileishmanial Effect of 1,5- and 1,8-Substituted Fused Naphthyridines
Molecules, Vol. 29, Núm. 1
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Aza-Povarov Reaction. A Method for the Synthesis of Fused Tetracyclic Chromeno[4,3-d]pyrido[1,2-a]pyrimidines
Journal of Organic Chemistry, Vol. 89, Núm. 2, pp. 1099-1107
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Diastereoselective ZnCl2-Mediated Joullié–Ugi Three-Component Reaction for the Preparation of Phosphorylated N-Acylaziridines from 2H-Azirines
Molecules, Vol. 29, Núm. 5
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Synthesis, biological and computational evaluation of novel cyanomethyl vinyl ether derivatives
Frontiers in Pharmacology, Vol. 15
2023
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Chiral self-recognition in a bispericyclic cyclodimerisation reaction of 1-azadienes
Organic Chemistry Frontiers, Vol. 10, Núm. 24, pp. 6103-6111
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Efficient AntiMycolata Agents by Increasing the Lipophilicity of Known Antibiotics through Multicomponent Reactions
Antibiotics, Vol. 12, Núm. 1
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Gel-Free Tools for Quick and Simple Screening of Anti-Topoisomerase 1 Compounds
Pharmaceuticals, Vol. 16, Núm. 5
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Synthesis and Characterization of a New Series of Bis(allylic-α-aminophosphonates) under Mild Reaction Conditions
Molecules, Vol. 28, Núm. 12
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The Intramolecular Povarov Tool in the Construction of Fused Nitrogen-Containing Heterocycles
Topics in Current Chemistry, Vol. 381, Núm. 4
2022
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An overview of the applications of chiral phosphoric acid organocatalysts in enantioselective additions to C 00000000 00000000 00000000 00000000 11111111 00000000 11111111 00000000 00000000 00000000 O and C N bonds
Organic Chemistry Frontiers, Vol. 9, Núm. 22, pp. 6331-6399
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Diethyl(benzamido(diisopropoxyphosphoryl)methyl) phosphonate
MolBank, Vol. 2022, Núm. 3
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Exploring the Synthetic Potential of γ-Lactam Derivatives Obtained from a Multicomponent Reaction. Applications as Antiproliferative Agents
Molecules, Vol. 27, Núm. 11
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Hydrogen sulphide-triggered theranostic prodrugs based on the dynamic chemistry of tetrazines
Chemical Communications, Vol. 58, Núm. 36, pp. 5518-5521
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Microwave-assisted palladium catalysed C-H acylation with aldehydes: Synthesis and diversification of 3-acylthiophenes
Organic and Biomolecular Chemistry, Vol. 20, Núm. 4, pp. 852-861
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Multicomponent Synthesis of Unsaturated γ-Lactam Derivatives. Applications as Antiproliferative Agents through the Bioisosterism Approach: Carbonyl vs. Phosphoryl Group
Pharmaceuticals, Vol. 15, Núm. 5
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Sc(OTf)3-Mediated [4 + 2] Annulations of N-Carbonyl Aryldiazenes with Cyclopentadiene to Construct Cinnoline Derivatives: Azo-Povarov Reaction
Journal of Organic Chemistry, Vol. 87, Núm. 17, pp. 11583-11592
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Synthesis of Tetrasubstituted Phosphorus Analogs of Aspartic Acid as Antiproliferative Agents
Molecules, Vol. 27, Núm. 22
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Synthesis of hybrid phosphorated indenoquinolines and biological evaluation as topoisomerase I inhibitors and antiproliferative agents
Bioorganic and Medicinal Chemistry Letters, Vol. 57
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The design and discovery of topoisomerase I inhibitors as anticancer therapies
Expert Opinion on Drug Discovery, Vol. 17, Núm. 6, pp. 581-601