Síntesis Orgánica en Química Médica
Publicaciones (243) Publicaciones en las que ha participado algún/a investigador/a
2022
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An overview of the applications of chiral phosphoric acid organocatalysts in enantioselective additions to C 00000000 00000000 00000000 00000000 11111111 00000000 11111111 00000000 00000000 00000000 O and C N bonds
Organic Chemistry Frontiers, Vol. 9, Núm. 22, pp. 6331-6399
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Diethyl(benzamido(diisopropoxyphosphoryl)methyl) phosphonate
MolBank, Vol. 2022, Núm. 3
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Exploring the Surface of the Ectodomain of the PD-L1 Immune Checkpoint with Small-Molecule Fragments
ACS Chemical Biology, Vol. 17, Núm. 9, pp. 2655-2663
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Exploring the Synthetic Potential of γ-Lactam Derivatives Obtained from a Multicomponent Reaction. Applications as Antiproliferative Agents
Molecules, Vol. 27, Núm. 11
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Hydrogen sulphide-triggered theranostic prodrugs based on the dynamic chemistry of tetrazines
Chemical Communications, Vol. 58, Núm. 36, pp. 5518-5521
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Multicomponent Synthesis of Unsaturated γ-Lactam Derivatives. Applications as Antiproliferative Agents through the Bioisosterism Approach: Carbonyl vs. Phosphoryl Group
Pharmaceuticals, Vol. 15, Núm. 5
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Sc(OTf)3-Mediated [4 + 2] Annulations of N-Carbonyl Aryldiazenes with Cyclopentadiene to Construct Cinnoline Derivatives: Azo-Povarov Reaction
Journal of Organic Chemistry, Vol. 87, Núm. 17, pp. 11583-11592
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Synthesis of Tetrasubstituted Phosphorus Analogs of Aspartic Acid as Antiproliferative Agents
Molecules, Vol. 27, Núm. 22
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Synthesis of hybrid phosphorated indenoquinolines and biological evaluation as topoisomerase I inhibitors and antiproliferative agents
Bioorganic and Medicinal Chemistry Letters, Vol. 57
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The design and discovery of topoisomerase I inhibitors as anticancer therapies
Expert Opinion on Drug Discovery, Vol. 17, Núm. 6, pp. 581-601
2021
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5-ethoxy-1-(4-methoxyphenyl)-5-methyl-3-phenylimidazolidine-2,4-dione
MolBank, Vol. 2021, Núm. 2
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A dual-sensor-based screening system for in vitro selection of tdp1 inhibitors
Sensors, Vol. 21, Núm. 14
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A multicomponent protocol for the synthesis of highly functionalized γ-lactam derivatives and their applications as antiproliferative agents
Pharmaceuticals, Vol. 14, Núm. 8
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A patent review of topoisomerase I inhibitors (2016–present)
Expert Opinion on Therapeutic Patents, Vol. 31, Núm. 6, pp. 473-508
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Asymmetric synthesis of tetrasubstituted α-aminophosphonic acid derivatives
Molecules, Vol. 26, Núm. 11
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Design, synthesis and cytotoxic evaluation of diphenyl(quinolin-8-yl)phosphine oxides
Tetrahedron Letters, Vol. 70
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ENANTIOSELECTIVE SYNTHESIS OF UNSATURATED γ-LACTAMS
Targets in Heterocyclic Systems, Vol. 25, pp. 22-52
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Fused chromeno and quinolino[1,8]naphthyridines: Synthesis and biological evaluation as topoisomerase I inhibitors and antiproliferative agents
Bioorganic and Medicinal Chemistry, Vol. 40
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Hybrid quinolinyl phosphonates as heterocyclic carboxylate isosteres: Synthesis and biological evaluation against topoisomerase 1b (top1b)
Pharmaceuticals, Vol. 14, Núm. 8
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Modulation of conductivity of alginate hydrogels containing reduced graphene oxide through the addition of proteins
Pharmaceutics, Vol. 13, Núm. 9