Publikationen (104) Publikationen, an denen Forscher/innen teilgenommen haben

2022

  1. Fine-tuning of the Hsc70-based Human Protein Disaggregase Machinery by the Distinctive C-terminal Extension of Apg2

    Journal of Molecular Biology, Vol. 434, Núm. 22

  2. Quantitative super-resolution imaging of pathological aggregates reveals distinct toxicity profiles in different synucleinopathies

    Proceedings of the National Academy of Sciences of the United States of America, Vol. 119, Núm. 41

2021

  1. All-or-none amyloid disassembly via chaperone-triggered fibril unzipping favors clearance of α-synuclein toxic species

    Proceedings of the National Academy of Sciences of the United States of America, Vol. 118, Núm. 36

  2. Inhibition of the human hsc70 system by small ligands as a potential anticancer approach

    Cancers, Vol. 13, Núm. 12

  3. Oligonucleotide-directed protein threading through a rigid nanopore

    Methods in Molecular Biology (Humana Press Inc.), pp. 135-144

  4. Single-aminoacid discrimination in proteins with homogeneous nanopore sensors and neural networks

    Biosensors and Bioelectronics, Vol. 180

  5. The emerging landscape of single-molecule protein sequencing technologies

    Nature Methods, Vol. 18, Núm. 6, pp. 604-617

  6. Truncation‐driven lateral association of α‐synuclein hinders amyloid clearance by the Hsp70‐based disaggregase

    International Journal of Molecular Sciences, Vol. 22, Núm. 23

  7. Unzipping the secrets of amyloid disassembly by the human disaggregase

    Cells, Vol. 10, Núm. 10

  8. Use of pore-forming toxins to study co-translocational protein folding

    Methods in Enzymology (Academic Press Inc.), pp. 635-649

2020

  1. Extraction and Refolding Determinants of Chaperone-Driven Aggregated Protein Reactivation

    Journal of Molecular Biology, Vol. 432, Núm. 10, pp. 3239-3250

  2. Free-energy landscapes of membrane co-translocational protein unfolding

    Communications Biology, Vol. 3, Núm. 1

  3. Transmembrane protein rotaxanes reveal kinetic traps in the refolding of translocated substrates

    Communications Biology, Vol. 3, Núm. 1

2019

  1. Regulation of Human Hsc70 ATPase and Chaperone Activities by Apg2: Role of the Acidic Subdomain

    Journal of Molecular Biology, Vol. 431, Núm. 2, pp. 444-461

  2. Structural and functional insights on the roles of molecular chaperones in the mistargeting and aggregation phenotypes associated with primary hyperoxaluria type I

    Advances in Protein Chemistry and Structural Biology (Academic Press Inc.), pp. 119-152

  3. Structural insights into the ability of nucleoplasmin to assemble and chaperone histone octamers for DNA deposition

    Scientific Reports, Vol. 9, Núm. 1

  4. The complex phosphorylation patterns that regulate the activity of Hsp70 and its cochaperones

    International Journal of Molecular Sciences, Vol. 20, Núm. 17

2018

  1. Activation of the DnaK-ClpB Complex is Regulated by the Properties of the Bound Substrate

    Scientific Reports, Vol. 8, Núm. 1

  2. DNA-binding miniproteins based on zinc fingers. Assessment of the interaction using nanopores

    Chemical Science, Vol. 9, Núm. 17, pp. 4118-4123

2017

  1. Label-Free, Multiplexed, Single-Molecule Analysis of Protein-DNA Complexes with Nanopores

    ACS Nano, Vol. 11, Núm. 6, pp. 5815-5825