Protein Folding and Role of Molecular Chaperones
Publicaciones (104) Publicaciones en las que ha participado algún/a investigador/a
2022
-
Fine-tuning of the Hsc70-based Human Protein Disaggregase Machinery by the Distinctive C-terminal Extension of Apg2
Journal of Molecular Biology, Vol. 434, Núm. 22
-
Quantitative super-resolution imaging of pathological aggregates reveals distinct toxicity profiles in different synucleinopathies
Proceedings of the National Academy of Sciences of the United States of America, Vol. 119, Núm. 41
2021
-
All-or-none amyloid disassembly via chaperone-triggered fibril unzipping favors clearance of α-synuclein toxic species
Proceedings of the National Academy of Sciences of the United States of America, Vol. 118, Núm. 36
-
Inhibition of the human hsc70 system by small ligands as a potential anticancer approach
Cancers, Vol. 13, Núm. 12
-
Oligonucleotide-directed protein threading through a rigid nanopore
Methods in Molecular Biology (Humana Press Inc.), pp. 135-144
-
Single-aminoacid discrimination in proteins with homogeneous nanopore sensors and neural networks
Biosensors and Bioelectronics, Vol. 180
-
The emerging landscape of single-molecule protein sequencing technologies
Nature Methods, Vol. 18, Núm. 6, pp. 604-617
-
Truncation‐driven lateral association of α‐synuclein hinders amyloid clearance by the Hsp70‐based disaggregase
International Journal of Molecular Sciences, Vol. 22, Núm. 23
-
Unzipping the secrets of amyloid disassembly by the human disaggregase
Cells, Vol. 10, Núm. 10
-
Use of pore-forming toxins to study co-translocational protein folding
Methods in Enzymology (Academic Press Inc.), pp. 635-649
2020
-
Extraction and Refolding Determinants of Chaperone-Driven Aggregated Protein Reactivation
Journal of Molecular Biology, Vol. 432, Núm. 10, pp. 3239-3250
-
Free-energy landscapes of membrane co-translocational protein unfolding
Communications Biology, Vol. 3, Núm. 1
-
Transmembrane protein rotaxanes reveal kinetic traps in the refolding of translocated substrates
Communications Biology, Vol. 3, Núm. 1
2019
-
Regulation of Human Hsc70 ATPase and Chaperone Activities by Apg2: Role of the Acidic Subdomain
Journal of Molecular Biology, Vol. 431, Núm. 2, pp. 444-461
-
Structural and functional insights on the roles of molecular chaperones in the mistargeting and aggregation phenotypes associated with primary hyperoxaluria type I
Advances in Protein Chemistry and Structural Biology (Academic Press Inc.), pp. 119-152
-
Structural insights into the ability of nucleoplasmin to assemble and chaperone histone octamers for DNA deposition
Scientific Reports, Vol. 9, Núm. 1
-
The complex phosphorylation patterns that regulate the activity of Hsp70 and its cochaperones
International Journal of Molecular Sciences, Vol. 20, Núm. 17
2018
-
Activation of the DnaK-ClpB Complex is Regulated by the Properties of the Bound Substrate
Scientific Reports, Vol. 8, Núm. 1
-
DNA-binding miniproteins based on zinc fingers. Assessment of the interaction using nanopores
Chemical Science, Vol. 9, Núm. 17, pp. 4118-4123
2017
-
Label-Free, Multiplexed, Single-Molecule Analysis of Protein-DNA Complexes with Nanopores
ACS Nano, Vol. 11, Núm. 6, pp. 5815-5825