Validación Rasch del Keratoconus End-Points Assessment Questionnaire en población española con queratocono
- Kepa Balparda 8
- Luis García-Onrubia 89
- Fco Javier Valentín-Bravo 1
- Mariana Escobar-Giraldo 2
- Manuel Caro-Magdaleno 36
- A. Acera Osa 467
- Jesús M. Merayo-Lloves 56
- David José Galarreta 68
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1
Hospital Universitari Germans Trias i Pujol
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2
Universidad Pontificia Bolivariana
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- 3 Hospital Universitario Virgen Macarena., Sevilla, España
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4
Universidad del País Vasco/Euskal Herriko Unibertsitatea
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Universidad del País Vasco/Euskal Herriko Unibertsitatea
Lejona, España
- 5 Instituto Fernández Vega, Oviedo, Asturias, España
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Instituto de Salud Carlos III
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Ikerbasque, Fundación Vasca para la Ciencia
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Ikerbasque, Fundación Vasca para la Ciencia
Bilbao, España
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8
Hospital Universitario de Valladolid
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9
Fundación Jiménez Díaz
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ISSN: 0365-6691
Year of publication: 2024
Volume: 99
Issue: 8
Pages: 323-330
Type: Article
More publications in: Archivos de la Sociedad Española de Oftalmologia
Abstract
Objective To carry out a methodologically complete validation of the Spanish version of the Keratoconus End-Points Assessment Questionnaire (KEPAQ) in a Spanish population with keratoconus. Method Analytical, prospective study, including patients with keratoconus without previous surgical history, in which a measurement of quality of life was performed using the KEPAQ questionnaire, a complete exploration of the anterior pole and a corneal elevation topography with the Galilei™ G6 topographer. The evaluation of the psychometric characteristics of the scale in the studied population was carried out using Rasch modeling. Results A total of 140 patients with keratoconus were included, with a median age of 26.0 years, the majority (57.6%) being men. For the KEPAQ-E subscale, the median score was 69.3, with a reliability of 0.85 and an eigenvalue of the first contrast of 2.34. For the KEPAQ-F, the median score was 56.4, with a reliability of 0.88 and an eigenvalue of 2.00. All infit and outfit parameters were within normal limits for both subscales. A significant evaluation was found between the evaluations of both subscales (rho = 0.696; p < 0.001). The evaluations of the subscales and various clinical and tomographic characteristics showed a significant classification between them (p value between 0.048 y 0.001). Conclusion The KEPAQ is a psychometrically robust and valid scale to evaluate quality of life in the Spanish population with keratoconus. This questionnaire can be easily used for both clinical and research aims.