Anemias Sideroblásticas
- A. Cánovas Fernández 1
- Ramiro de la Prieta 1
- Juan José Alonso Alonso 1
- C. Ruiz 1
- T. Pereira 1
- C. Aguirre 1
- 1 Hospital de Cruces. Barakaldo
ISSN: 0304-4858, 2173-2302
Year of publication: 2002
Volume: 99
Issue: 2
Pages: 44-48
Type: Article
More publications in: Gaceta médica de Bilbao: Revista oficial de la Academia de Ciencias Médicas de Bilbao. Información para profesionales sanitarios
Abstract
The common feature of all sideroblastic anemias is the alteration of hem synthesis in erytroid precursors of the bone marrow; this gives rise to the deposit of iron inside the motochondria, leading to the formation of the so called ring sideroblasts. Causes are diverse though acquired anemias are far more frequent, for example myelodisplastic syndromes which present a clonal alteration of erythoripiesis. Seldom we find hereditary anemias, mostly affecting males, following a pattern of X-linked transmission. Finally we should point some reversible ones, such as the associated with alcohol abuse and some drug intake. Treatment depends on the cause but in every case it is required besides controlling symptomatic anemia to forsee organic damage due to iron overcharge.