Premio Nobel 2021 en Medicina y FisiologíaLa importancia de los receptores somatosensoriales en nuestra relación con el entorno
- 1 Departamento de Neurociencias en la Facultad de Medicina de la Universidad del País Vasco (UPV/EHU)
- 2 Grupo de enfermedades neurodegeneativas del Instituto de Investigación Biocruces-Bizkaia y Neurotek en el Hospital San Juan de Dios de Santurtzi
ISSN: 0304-4858, 2173-2302
Año de publicación: 2022
Volumen: 119
Número: 2
Páginas: 84-87
Tipo: Artículo
Otras publicaciones en: Gaceta médica de Bilbao: Revista oficial de la Academia de Ciencias Médicas de Bilbao. Información para profesionales sanitarios
Referencias bibliográficas
- Coste B, Mathur J, Schmidt M, et al. Piezo1 and Piezo2 are essential components of distinct mechanically activated cation channels. Science 2010;330:55-60.
- Caterina MJ, Schumacher MA, Tominaga M, Ro-sen TA, Levine JD, Julius D. The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature 1997;389:816-24.
- Munger BL, Ide C. The structure and function of cutaneous sensory receptors. Arch Histol Cytol 1988;51:1-34.
- Gonzalez-Ramirez R, Chen Y, Liedtke WB, Morales-Lazaro SL. TRP Channels and Pain. In: Emir TLR, ed. Neurobiology of TRP Channels. Boca Raton (FL)2017:125-47.
- Julius D. TRP channels and pain. Annu Rev Cell Dev Biol 2013;29:355- 84.
- Basbaum AI, Bautista DM, Scherrer G, Julius D. Cellular and molecular mechanisms of pain. Cell 2009;139:267-84.
- Thebault S. Minireview: Insights into the role of TRP channels in the retinal circulation and function. Neurosci Lett 2021;765:136285.
- Cavanaugh DJ, Lee H, Lo L, et al. Distinct subsets of unmyelinated primary sensory fibers mediate behavioral responses to noxious thermal and mechanical stimuli. Proc Natl Acad Sci U S A 2009;106:9075-80.
- Hwang SJ, Oh JM, Valtschanoff JG. Expression of the vanilloid receptor TRPV1 in rat dorsal root ganglion neurons supports different roles of the receptor in visceral and cutaneous afferents. Brain Res 2005;1047:261-6.
- Cavanaugh DJ, Chesler AT, Jackson AC, et al. Trpv1 reporter mice reveal highly restricted brain distribution and functional expression in arteriolar smooth muscle cells. J Neurosci 2011;31:5067-77.
- Weyer-Menkhoff I, Pinter A, Schlierbach H, Schanzer A, Lotsch J. Epidermal expression of human TRPM8, but not of TRPA1 ion channels, is associated with sensory responses to local skin cooling. Pain 2019;160:2699- 709.
- Woo SH, Lukacs V, de Nooij JC, et al. Piezo2 is the principal mechanotransduction channel for proprioception. Nat Neurosci 2015;18:1756- 62.
- Klaniewska M, Jedrzejowska M, Rydzanicz M, et al. Case Report: Further Delineation of Neurological Symptoms in Young Children Caused by Compound Heterozygous Mutation in the PIE-ZO2 Gene. Front Genet 2021;12:620752.
- Shin SM, Moehring F, Itson-Zoske B, et al. Piezo2 mechanosensitive ion channel is located to sen-sory neurons and nonneuronal cells in rat peripheral sensory pathway: implications in pain. Pain 2021;162:2750-68.
- Marshall KL, Saade D, Ghitani N, et al. PIEZO2 in sensory neurons and urothelial cells coordinates urination. Nature 2020;588:290-5.
- Stocker SD, Sved AF, Andresen MC. Missing pieces of the Piezo1/Piezo2 baroreceptor hypothesis: an autonomic perspective. J Neurophysiol 2019;122:1207-12.
- Zeng WZ, Marshall KL, Min S, et al. PIEZOs mediate neuronal sensing of blood pressure and the baroreceptor reflex. Science 2018;362:464-7.
- Della Pietra A, Mikhailov N, Giniatullin R. The Emerging Role of Mechanosensitive Piezo Channels in Migraine Pain. Int J Mol Sci 2020;21.
- Mikhailov N, Leskinen J, Fagerlund I, et al. Mechanosensitive meningeal nociception via Piezo channels: Implications for pulsatile pain in migraine? Neuropharmacology 2019;149:113-23.
- Morozumi W, Aoshima K, Inagaki S, et al. Piezo 1 is involved in intraocular pressure regulation. J Pharmacol Sci 2021;147:211-21