Urte bat baino gutxiagoko umeengan agertutako nerbio-sistema zentraleko tumoreakberrikuspena Gurutzetako Unibertsitate Ospitalean eta literaturan
- Edurne Ruiz de Gopegui
- Gaizka Bilbao Barandica
- Lara Galbarriartu
- Gregorio Catalán Uribarrena
- Miguel García-Ariza
- Itziar Astigarraga Aguirre
- Laura Zaldumbide Dueñas
- Ainara Dolado
- Iñigo Pomposo Gastelu
ISSN: 2530-9412
Year of publication: 2017
Volume: 1
Issue: 1
Pages: 26-32
Type: Article
More publications in: Osagaiz: osasun-zientzien aldizkaria
Abstract
Here, we present a review of CNS tumors diagnosed in an under one year-old population in Cruces University Hospital. We studied under one year-old patients diagnosed between 2001 and 2016 in Cruces University Hospital, and reviewed location, approach, presence/absence of hydrocephalus, survival and follow-up. Sixteen under one year-old patients were diagnosed among a series of 158 <14 year old children during that period. Fourteen patients had supratentorial tumors, 1 had an infratentorial tumor and one had an intraspinal cervical tumor. The sample included 10 gliomas (2 high grade, 8 low grade), 3 infratentorial primitive neuroectodermal tumors (PNET), 1 atypical choroidal plexus papilloma, 1 atypical teratoid/rhabdoid tumor, 1 supratentorial PNET and 1 neuroectodermal melanocytic tumor. Fourteen patients were operated on; in twelve of them we employed craniotomy with variable resection. Two of these needed consecutive craniotomies. In two patients, stereotactic biopsy was carried out due to the suspicion of an optic pathway glioma. Two patients were not amenable for surgical resection or biopsy and thus were not operated. Except for one patient who is alive after a follow-up of five years, the rest of the patients diagnosed of high-grade tumors died during follow up, two of them passing away during the surgical procedure. All patients diagnosed with a low-grade tumor are alive with a median follow-up of 3.8 years, except for one patient who died four years post-operation. Congenital tumors show a different pattern than tumors in other pediatric ages. The prognosis of high grade lesions continues to be discouraging despite apparent improvements.