Kannabinoide berriaksegurtasun eta eraginkortasun terapeutikoaren bila

  1. Erik Aostri
  2. Joseba Pineda
  3. Aitziber Mendiguren
Journal:
Ekaia: Euskal Herriko Unibertsitateko zientzi eta teknologi aldizkaria

ISSN: 0214-9001

Year of publication: 2017

Issue: 31

Pages: 7-20

Type: Article

DOI: 10.1387/EKAIA.16320 DIALNET GOOGLE SCHOLAR lock_openOpen access editor

More publications in: Ekaia: Euskal Herriko Unibertsitateko zientzi eta teknologi aldizkaria

Abstract

Cannabis sativa plant contains non-psychoactive phytocannabinoids including cannabidiol, cannabigerol or Δ9-tetrahydrocannabivarin. Unlike classical cannabinoids (i.e Δ9-THC) most of these compounds bind with low affinity to cannabinoid receptors (CB), which seems to be the reason for their lack of psychoactive effect. Preliminary studies performed in humans and animals demonstrated that these cannabinoids have therapeutic properties. Different targets and mechanisms have been proposed to explain their effects such as activation of serotonergic receptors or modulation of different enzymes.