Analisi farmakozinetiko/farmakodinamikoa antimikrobianoen erabilera hobetzeko gaixo larrietan

  1. Amaia Soraluce Olañeta 1
  2. Alicia Rodriguez Gascón 1
  3. Arantxazu Isla Ruiz 1
  1. 1 Farmazia Fakultatea, Lascaray-Ikergunea. Euskal Herriko Unibertsitatea (UPV/EHU)
Journal:
Ekaia: Euskal Herriko Unibertsitateko zientzi eta teknologi aldizkaria

ISSN: 0214-9001

Year of publication: 2018

Issue: 33

Pages: 19-33

Type: Article

DOI: 10.1387/EKAIA.17849 DIALNET GOOGLE SCHOLAR lock_openOpen access editor

More publications in: Ekaia: Euskal Herriko Unibertsitateko zientzi eta teknologi aldizkaria

Abstract

Nowadays, the treatment of infectious diseases has become a global health issue, due to multi-resistant antibiotic bacteria. The lack of new antibiotics enhances urgent need for current antimicrobials’ dosing regimens optimization. This could be-come an extremely challenging duty when treating some kind of patients, such as the critically ill; as due to their physiophatological situation, both pharmacokinetics and pharmacodynamics might be altered. PK/PD analysis, together with Monte Carlo Sim-ulation, might be a useful tool in order to optimize dosing regimens of antibiotic agents and, therefore, improve clinical outcome and diminish emergence of resistances.

Data source: Dialnet