Publications (62) Publications de MARIA GLORIA RUBIALES ALCAINE

2021

  1. A patent review of topoisomerase I inhibitors (2016–present)

    Expert Opinion on Therapeutic Patents, Vol. 31, Núm. 6, pp. 473-508

  2. Fused chromeno and quinolino[1,8]naphthyridines: Synthesis and biological evaluation as topoisomerase I inhibitors and antiproliferative agents

    Bioorganic and Medicinal Chemistry, Vol. 40

2020

  1. Fused 1,5-Naphthyridines: Synthetic Tools and Applications

    Molecules (Basel, Switzerland), Vol. 25, Núm. 15

  2. Novel phosphine sulphide gold(i) complexes: topoisomerase I inhibitors and antiproliferative agents

    Dalton Transactions, Vol. 49, Núm. 23, pp. 7852-7861

  3. Synthesis of novel hybrid quinolino[4,3-b][1,5]naphthyridines and quinolino[4,3-b][1,5]naphthyridin-6(5H)-one derivatives and biological evaluation as topoisomerase I inhibitors and antiproliferatives

    European Journal of Medicinal Chemistry, Vol. 195

  4. Synthetic strategies, reactivity and applications of 1,5-naphthyridines

    Molecules, Vol. 25, Núm. 14

2019

  1. Antileishmanial activity of new hybrid tetrahydroquinoline and quinoline derivatives with phosphorus substituents

    European Journal of Medicinal Chemistry, Vol. 162, pp. 18-31

  2. Reaction of phosphinyl nitrosoalkenes with electron-rich heterocycles

    Phosphorus, Sulfur and Silicon and the Related Elements, Vol. 194, Núm. 4-6, pp. 545-549

  3. Straightforward synthesis and biological evaluation as topoisomerase I inhibitors and antiproliferative agents of hybrid Chromeno[4,3-b][1,5]Naphthyridines and Chromeno[4,3-b][1,5]Naphthyridin-6-ones

    European Journal of Medicinal Chemistry, Vol. 178, pp. 752-766

2018

  1. Density Functional Theory Study on the Demethylation Reaction between Methylamine, Dimethylamine, Trimethylamine, and Tamoxifen Catalyzed by a Fe(IV)-Oxo Porphyrin Complex

    Journal of Physical Chemistry A, Vol. 122, Núm. 6, pp. 1658-1671

  2. Novel topoisomerase I inhibitors. Syntheses and biological evaluation of phosphorus substituted quinoline derivates with antiproliferative activity

    European Journal of Medicinal Chemistry, Vol. 149, pp. 225-237

  3. Substituted 1,5-naphthyridine derivatives as novel antileishmanial agents. Synthesis and biological evaluation

    European Journal of Medicinal Chemistry, Vol. 152, pp. 137-147

  4. Synthesis of novel antiproliferative hybrid bis-(3-indolyl)methane phosphonate derivatives

    European Journal of Medicinal Chemistry, Vol. 158, pp. 874-883

2017

  1. ACTIVE METHODOLOGIES FOR SOLVING CLINICAL CASES: STUDENT'S FEEDBACK

    10TH INTERNATIONAL CONFERENCE OF EDUCATION, RESEARCH AND INNOVATION (ICERI2017)

  2. Advantages of an optical nanosensor system for the mechanistic analysis of a novel topoisomerase i targeting drug: A case study

    Nanoscale, Vol. 9, Núm. 5, pp. 1886-1895

  3. Reaction of phosphinylated nitrosoalkenes with electron-rich heterocycles. Electrophilic aromatic substitution vs. cycloaddition

    Organic and Biomolecular Chemistry, Vol. 15, Núm. 3, pp. 662-671

  4. Reliable Synthesis of Phosphino- and Phosphine Sulfide-1,2,3,4-Tetrahydroquinolines and Phosphine Sulfide Quinolines

    European Journal of Organic Chemistry, Vol. 2017, Núm. 20, pp. 2916-2924

  5. Study of the Hetero-[4+2]-Cycloaddition Reaction of Aldimines and Alkynes. Synthesis of 1,5-Naphthyridine and Isoindolone Derivatives

    Journal of Organic Chemistry, Vol. 82, Núm. 12, pp. 6379-6387

2016

  1. Antileishmanial effect of new indeno-1,5-naphthyridines, selective inhibitors of Leishmania infantum type IB DNA topoisomerase

    European Journal of Medicinal Chemistry, Vol. 124, pp. 740-749

  2. Synthesis and biological evaluation of indeno[1,5]naphthyridines as topoisomerase i (TopI) inhibitors with antiproliferative activity

    European Journal of Medicinal Chemistry, Vol. 115, pp. 179-190