Development of scaffolds based on natural materials for tendon tissue regeneration

  1. Ruiz Alonso 123
  2. Lafuente Merchan Ma 123
  3. Gallego I 123
  4. Saenz Del Burgo L 123
  5. Pedraz JL 123
  1. 1 Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN),Vitoria-Gasteiz, Spain
  2. 2 Bioaraba Health Research Institute, NanoBioCel Research Group, E-01009 Vitoria-Gasteiz, Spain
  3. 3 NanoBiocel Group, Laboratory of Pharmaceutics, School of Pharmacy, University of the Basque Country (UPV/ EHU), Vitoria-Gasteiz, Spain
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Revue:
RESCIFAR Revista Española de Ciencias Farmacéuticas

ISSN: 2660-6356

Année de publication: 2021

Titre de la publication: XV CONGRESO DE LA SOCIEDAD ESPAÑOLA DE FARMACIA INDUSTRIA Y GALÉNICA

Volumen: 2

Número: 2

Pages: 6-8

Type: Article

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D'autres publications dans: RESCIFAR Revista Española de Ciencias Farmacéuticas

Résumé

Tendon injuries represent a clinical burden on health systems globally. 3D bioprinting could help for the development of scaffolds whose characteristics resemble those of the native tendon. In this study, an ink based on natural materials was developed for tendon tissue regeneration. That ink was characterized and used to print scaffolds by 3D printing. Swelling and degradation rate assays were performed to predict the possible behaviour of the scaffolds in vivo. Finally, tenocytes were incorporated into the inks and 3D bioprinted. The viability and metabolic activity of tenocytes in the scaffold were analyzed.

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